The material on this web site including female hormones is offered to you for informational purposes only and is not meant to be interpreted as medical advice to diagnose, treat or cure any hormone imbalance. You should consult with a qualified health professional whenever your health is in question.
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Immune System Etc.com focus: immune system information, the immune response, immune system support, what you need to be aware of when you boost the immune system, hormone balance, female & Male hormones: progesterone, estrogen, combating immune system stressors, what weakens the immune system, what strengthens the immune system, immune system deficiencies including auto immune disorders, and how you can help the body heal.
Autoimmune Diseases - Female & Male Hormones
Progesterone & Estrogen
A factor in autoimmune diseases?
“The immune system is also affected by hormone status.” Dr. John Lee

Dr. John Lee was considered to be the leading expert on the effects and use of the female  & male hormone progesterone. Much research has been done world wide supporting his statements, and conversely, his statements reflect much of the research done throughout the world.

The debunking of the health claims and dangers of HRT (Hormone Replacement Therapy for women) is due in large measure to his ground-breaking efforts to find the truth.

He has written several books on the topic that you’ll find listed at the end of these excerpts. Dr. Lee lectured throughout the United States and around the world.

“One of progesterone’s most important and powerful roles in the body is to balance or oppose the estrogen. When our progesterone levels are in balance, excess estrogen is better handled.” Dr. John Lee
women who use hormone replacement therapy containing estrogen are more likely to get lupus.”
Dr. John Lee
Immune System
Immune Stressors
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Dr. John Lee's Books on Hormones, Menapause, Breast Cancer, etc.
While most of Dr. Lee’s work has focused on women as women are more directly affected by estrogen, men are hardly exempt. He is currently working on a book relating specifically to men and hormone balance.

The following are excerpts from his books that will help explain the dynamics between autoimmune disease and female hormones, specifically progesterone as related to estrogen.

“It’s not uncommon for women with these disorders [including but not limited to – rheumatoid arthritis, sjogren’s syndrome, hashimoto’s thyroiditis, graves disease, lupus, rosacea] to find that their symptoms gradually resolve when they balance their hormones with progesterone.

Such cases strongly suggest that the female hormone progesterone protects against autoimmune disorders caused by excessive estrogens.”

Dr. Lee states in a list of estrogen and progesterone effects that estrogen increases the risk of autoimmune disorders while progesterone functions as a precursor of corticosteroids. Why this is important is reflected in the following…

“Autoimmune disorders in general are thought to be triggered by transient viruses in susceptible people; the virus triggers antibodies against some protein component of the virus. By some probably minor fluke, the antibodies attack similar proteins in certain body tissues… Corticosteroids block this attack by one’s own antibodies.”

“One can hypothesize that estrogen dominance may have had a hand in triggering the errant antibodies and thus correcting the estrogen dominance leads to gradual correction of the problem. Progesterone is also the main precursor of corticosteroids and in progesterone-deficient women, restoration of normal progesterone levels may enhance normal corticosteroid production, thus suppressing the autoimmune attack.”